Article
Evaluation of DNMT3A genetic polymorphisms as outcome predictors in AML patients.
Oncotarget - 13 Sept 2016
Yuan Xiao-Qing, Zhang Dao-Yu, Yan Han, Yang Yong-Long, Zhu Ke-Wei, Chen Yan-Hong, Li Xi, Yin Ji-Ye, Li Xiao-Lin, Zeng Hui, Chen Xiao-Ping
Abstract excerpt
DNMT3A mutation is known as a recurrent event in acute myelogenous leukemia (AML) patients. However, association between DNMT3A genetic polymorphisms and AML patients' outcomes is unknown. DNMT3A 11 SNPs (rs11695471, rs2289195, rs734693, rs2276598, rs1465825, rs7590760, , , , and ) were genotyped in 344 diagnostic non-FAB-M3 AML patients from southern China. Patients...
