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Article

Association between DNMT3A mutations and prognosis of adults with de novo acute myeloid leukemia: a systematic review and meta-analysis.

PloS one - 1 Jan 2014

Tie Ruxiu, Zhang Tiansong, Fu Huarui, Wang Limengmeng, Wang Yebo, He Ying, Wang Binsheng, Zhu Ni, Fu Shan, Lai Xiaoyu, Shi Jimin, Huang He

Abstract excerpt

BACKGROUND: DNA methyltransferase 3A (DNMT3A) mutations were considered to be independently associated with unfavorable prognosis in adults with de novo acute myeloid leukemia (AML), however, there are still debates on this topic. Here, we aim to further investigate the association between DNMT3A mutations and prognosis of patients with AML. METHODS: Eligible studies were identified from several data bases...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24936645
DOI: 10.1371/journal.pone.0093353
PMCID: PMC4061003

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EFS

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