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Article

Statistical Methods for Testing Genetic Pleiotropy.

Genetics - 1 Oct 2016

Schaid Daniel J, Tong Xingwei, Larrabee Beth, Kennedy Richard B, Poland Gregory A, Sinnwell Jason P

Abstract excerpt

Genetic pleiotropy is when a single gene influences more than one trait. Detecting pleiotropy and understanding its causes can improve the biological understanding of a gene in multiple ways, yet current multivariate methods to evaluate pleiotropy test the null hypothesis that none of the traits are associated with a variant; departures from the null could be driven by just one associated trait. A formal test of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27527515
DOI: 10.1534/genetics.116.189308
PMCID: PMC5068841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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