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Article

Determining Which Phenotypes Underlie a Pleiotropic Signal.

Genetic epidemiology - 1 Jul 2016

Majumdar Arunabha, Haldar Tanushree, Witte John S

Abstract excerpt

Discovering pleiotropic loci is important to understand the biological basis of seemingly distinct phenotypes. Most methods for assessing pleiotropy only test for the overall association between genetic variants and multiple phenotypes. To determine which specific traits are pleiotropic, we evaluate via simulation and application three different strategies. The first is model selection techniques based on the...

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Identifiers

PMID: 27238845
DOI: 10.1002/gepi.21973
PMCID: PMC4929010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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