Article
Endogenous androgen exposures and ischemic heart disease, a separate sample Mendelian randomization study.
International journal of cardiology - 1 Nov 2016
Zhao Jie V, Schooling C Mary
Abstract excerpt
BACKGROUND: Evolutionary biology suggests growth and reproduction trade-off against longevity. Correspondingly estrogen supplementation failed to increase lifespan. Testosterone supplementation is widely used by older men, although regulators have warned of its cardiovascular risk. No large trial of testosterone exists. We examined how genetic determinants of up-regulation (follicle-stimulating hormone (FSH)) and...
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