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Genetic analyses on the health impacts of testosterone highlight effects on female-specific diseases and sex differences

2021-04-26

Abstract excerpt

Testosterone (T) is linked with diverse characteristics of human health, yet, whether these associations reflect correlation or causation remains debated. Here, we provide a broad perspective on the role of T on complex diseases in both sexes leveraging genetic and health registry data from the UK Biobank and FinnGen (total N=625,650). We find genetically predicted T affects sex-biased and sex-specific traits, wit...

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Literature Corpus work
c77af0fe-5f2a-56b1-a668-38a870561cff
DOI
10.1101/2021.04.23.21255981
Open publication

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Genetic analyses on the health impacts of testosterone highlight effects on female-specific diseases and sex differencesDOI 10.1101/2021.04.23.21255981
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