Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic predictors of testosterone and their associations with cardiovascular disease and risk factors: A Mendelian randomization investigation.

International journal of cardiology - 15 Sept 2018

Schooling C Mary, Luo Shan, Au Yeung Shiu Lun, Thompson Deborah J, Karthikeyan Savita, Bolton Thomas R, Mason Amy M, Ingelsson Erik, Burgess Stephen

Abstract excerpt

BACKGROUND: Testosterone supplementation has been linked to increased cardiovascular disease risk in some observational studies. The causal role of testosterone can be investigated using a Mendelian randomization approach. METHODS AND RESULTS: We assessed genetic associations of variants in two gene regions (SHBG and JMJD1C) with several cardiovascular risk factors (lipids, adiponectin, blood pressure,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adiponectin
Share to Anthropometry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Artery Disease

Share to Jumonji Domain-Containing Histone Demethylases

Share to Oxidoreductases, N-Demethylating

Share to Stroke

Share to Testosterone

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 29804699
DOI: 10.1016/j.ijcard.2018.05.051
PMCID: PMC6024225

Genes

CAD
SHBG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic predictors of testosterone and their associations with cardiovascular disease and risk factors: A Mendelian randomization investigation.PMID 29804699Read ↗

Higher Circulating Testosterone Linked to Higher CAD Risk in Men: Mendelian Randomization and Survival Analyses.Semantic proximity Read ↗

Association of genetically predicted testosterone with thromboembolism, heart failure, and myocardial infarction: mendelian randomisation study in UK BiobankSemantic proximity Read ↗

Genetically predicted testosterone and cardiovascular risk factors in men: a Mendelian randomization analysis in the Guangzhou Biobank Cohort Study.Semantic proximity Read ↗

Genetic analyses on the health impacts of testosterone highlight effects on female-specific diseases and sex differencesSemantic proximity Read ↗

Investigating pleiotropic effects of statins on ischemic heart disease in the UK Biobank using Mendelian randomisationSemantic proximity Read ↗

Endogenous androgen exposures and ischemic heart disease, a separate sample Mendelian randomization study.Semantic proximity Read ↗

Genetic analyses implicate complex links between adult testosterone levels and health and diseaseSemantic proximity Read ↗

Genetically predicted sex hormone levels and health outcomes: phenome-wide Mendelian randomization investigationSemantic proximity Read ↗

Mendelian randomization suggests non-causal associations of testosterone with cardiometabolic risk factors and mortality.Semantic proximity Read ↗

Pleiotropic effects of statins on ischemic heart disease: a Mendelian Randomization study in the UK BiobankSemantic proximity Read ↗

Alcohol Consumption and Cardiovascular Disease: A Mendelian Randomization Study.Semantic proximity Read ↗

Causal effect of sex hormone-binding globulin and testosterone on coronary heart disease: A multivariable and network Mendelian randomization analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.