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Reproduction and longevity A Mendelian randomization study of gonadotropin-releasing hormone and ischemic heart disease

2018-11-19

Abstract excerpt

<h4>Background</h4> According to well-established evolutionary biology theory reproduction trades-off against longevity, implying that upregulating the reproductive axis might drive major diseases. We assessed whether the central driver of reproduction gonadotropin-releasing hormone 1 (GnRH1) had a causal effect on the leading cause of global morbidity and mortality, i.e. ischemic heart disease (IHD). As a contra...

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Literature Corpus work
d4b4dd29-fc44-5b8d-9188-32ffbeac85bb
DOI
10.1101/472548
Open publication

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Reproduction and longevity A Mendelian randomization study of gonadotropin-releasing hormone and ischemic heart diseaseDOI 10.1101/472548
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