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Investigating the association of testosterone with survival in men and women using a Mendelian randomization study in the UK Biobank

7 Jul 2021

Abstract excerpt

Life expectancy in the developed West is currently stagnated and remains shorter in men than women. Well-established evolutionary biology theory suggests lifespan trades-off against reproductive success, possibly sex-specifically. We examined whether a key driver of reproductive success, testosterone, affected survival using a Mendelian randomization longevity study in the UK Biobank to obtain unbiased estimates,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34234209
DOI: 10.1038/s41598-021-93360-z

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