Article
Allele-specific PCR method for identification of EGFR mutations in non-small cell lung cancer: formalin-fixed paraffin-embedded tissue versus fresh tissue.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie - 1 Jan 2016
Suciu Bogdan Andrei, Pap Zsuzsánna, Dénes Lóránd, Brînzaniuc Klara, Copotoiu Constantin, Pávai Zoltán
Abstract excerpt
UNLABELLED: The study of epidermal growth factor receptor (EGFR) gene mutations in lung adenocarcinoma patients has a special clinical significance in the selection of patients for tyrosine-kinase inhibitor therapy. The aim of this study was to identify patients with EGFR mutations using allele-specific polymerase chain reaction (PCR), from formalin-fixed paraffin-embedded (FFPE) tissue and fresh tissue (FT)....
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