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Article

Detection of common and less frequent EGFR mutations in cytological samples of lung cancer.

Acta cytologica - 1 Jan 2014

Rossi Esther D, Gerhard Renê, Cirnes Luis, Machado José Carlos, Schmitt Fernando

Abstract excerpt

OBJECTIVE: Lung cancer represents the leading cause of cancer death. EGFR mutations, detected in 10-40% of lung adenocarcinomas, are an essential key to therapeutic management. EGFR-activated mutations comprise mainly deletions in exon 19 and point mutations in exon 21. Although histology is the traditional method of detection, we investigated the role of cytology in EGFR mutations. STUDY DESIGN: A total of 774...

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Identifiers

PMID: 24924582
DOI: 10.1159/000363174

Genes

EGFR

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