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Article

Can EGFR mutation status be reliably determined in pre-operative needle biopsies from adenocarcinomas of the lung?

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Apr 2015

Lindahl Kim Hein, Sørensen Flemming Brandt, Jonstrup Søren Peter, Olsen Karen Ege, Loeschke Siegfried

Abstract excerpt

The identification of EGFR mutations in non-small-cell lung cancer is important for selecting patients, who may benefit from treatment with EGFR tyrosine kinase inhibitors. The analysis is usually performed on cytological aspirates and/or histological needle biopsies, representing a small fraction of the tumour volume. The aim of the present investigation was to evaluate the diagnostic performance of this...

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PMID: 25556929
DOI: 10.1111/apm.12350

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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