Article
Detection of an EGFR mutation in cytological specimens of lung adenocarcinoma.
Cytopathology : official journal of the British Society for Clinical Cytology - 1 Dec 2016
Mohar B, Smojver Ježek S, Rajković Molek K, Štemberger C, Kurpis M, Kupanovac Ž, Samaržija M, Jonjić N, Grahovac B
Abstract excerpt
OBJECTIVE: Epidermal growth factor receptors (EGFR) mutation status is crucial for the prediction of a tumour response to treatment with EGFR tyrosine kinase (EGFR-TK) inhibitors. The aim of the study was to establish a protocol for the detection of EGFR-activating somatic mutations on cytological samples collected using a standard bronchoscopy procedure and to determine the frequency of EGFR mutations among...
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