Article
Comparison of two methods to extract DNA from formalin-fixed, paraffin-embedded tissues and their impact on EGFR mutation detection in non-small cell lung carcinoma.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Hu Yu-Chang, Zhang Qian, Huang Yan-Hua, Liu Yu-Fei, Chen Hong-Lei
Abstract excerpt
OBJECTIVE: Molecular pathology tests are often carried for clinicopathological diagnosis and pathologists have established large collections of formalin-fixed, paraffin-embedded tissue (FFPE) banks. However, extraction of DNA from FFPE is a laborious and challenging for researchers in clinical laboratories. The aim of this study was to compare two widely used DNA extraction methods: using a QIAamp DNA FFPE kit...
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