Article
Clinical performance evaluation of the Idylla™ EGFR Mutation Test on formalin-fixed paraffin-embedded tissue of non-small cell lung cancer.
BMC cancer - 3 Apr 2020
Delgado-García Mercedes, Weynand Birgit, Gómez-Izquierdo Lourdes, Hernández María José, Blanco Ángela María, Varela Mar, Matias-Guiu Xavier, Nadal Ernest, Márquez-Lobo Bélgica, Alarcão Ana, de Álava Enrique, Biscuola Michele
Abstract excerpt
BACKGROUND: Detection of epidermal growth factor receptor (EGFR) mutations in exons 18-21 is recommended in all patients with advanced Non-small-cell lung carcinoma due to the demonstrated efficiency of the standard therapy with tyrosine kinase inhibitors in EGFR-mutated patients. Therefore, choosing a suitable technique to test EGFR mutational status is crucial to warrant a valid result in a short turnaround...
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