Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor-associated stromal cells as key contributors to the tumor microenvironment.

Breast cancer research : BCR - 11 Aug 2016

Bussard Karen M, Mutkus Lysette, Stumpf Kristina, Gomez-Manzano Candelaria, Marini Frank C

Abstract excerpt

The tumor microenvironment is a heterogeneous population of cells consisting of the tumor bulk plus supporting cells. It is becoming increasingly evident that these supporting cells are recruited by cancer cells from nearby endogenous host stroma and promote events such as tumor angiogenesis, proliferation, invasion, and metastasis, as well as mediate mechanisms of therapeutic resistance. In addition, recruited...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipocytes
Share to Cancer-Associated Fibroblasts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Endothelial Cells

Share to Exosomes

Share to MicroRNAs

Share to Stromal Cells

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 27515302
DOI: 10.1186/s13058-016-0740-2
PMCID: PMC4982339

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor-associated stromal cells as key contributors to the tumor microenvironment.PMID 27515302Read ↗

Targeting the tumor stroma for cancer therapySemantic proximity Read ↗

Diversity and Biology of Cancer-Associated FibroblastsSemantic proximity Read ↗

Cancer associated fibroblasts in cancer pathogenesis.Semantic proximity Read ↗

Cancer Associated Fibroblasts: The Architects of Stroma RemodelingSemantic proximity Read ↗

Role of the tumor microenvironment in cancer hallmarks and targeted therapy (Review)Semantic proximity Read ↗

Cancer-associated Fibroblasts: Origins, Heterogeneity and Functions in Tumor MicroenvironmentSemantic proximity Read ↗

Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biologySemantic proximity Read ↗

Cancer-Associated Fibroblasts in Solid Tumors and Sarcomas: Heterogeneity, Function, and Therapeutic ImplicationsSemantic proximity Read ↗

Cancer-associated fibroblasts as abettors of tumor progression at the crossroads of EMT and therapy resistanceSemantic proximity Read ↗

The extracellular matrix: A dynamic niche in cancer progressionSemantic proximity Read ↗

Tumor Microenvironment: A Complex Landscape of Cancer Development and Drug ResistanceSemantic proximity Read ↗

Tumor-host interactions: the role of inflammationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.