Role of the tumor microenvironment in cancer hallmarks and targeted therapy (Review)

Abstract excerpt

Genetic alterations drive tumor onset and progression. However, the cross‑talk between tumor cells and the benign components of the surrounding stroma can also promote the initiation, progression and metastasis of solid tumors. These cellular and non‑cellular stromal components form the tumor microenvironment (TME), which co‑evolves with tumor cells. Their dynamic and mutualistic interactions are currently...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cancer Cells and Metastasis
• Share to Cancer, Hypoxia, and Metabolism
• Share to Ferroptosis and cancer prognosis