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Article

Visualization and Manipulation of Cilia and Intraciliary Calcium in the Zebrafish Left-Right Organizer.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016

Yuan Shiaulou, Brueckner Martina

Abstract excerpt

Cilia play a key role in the determination of the left-right axis in vertebrates by generating and sensing flow of extraembryonic fluid at the left-right organizer (LRO). Perception of cilia-directed flow triggers a calcium signaling cascade which originates within the cilium itself and then is relayed into the surrounding mesendodermal tissue, thereby directing organ situs via the nodal pathway. Two types of...

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PMID: 27514920
DOI: 10.1007/978-1-4939-3789-9_9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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