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Article

TERT promoter mutations and chromosome 8p loss are characteristic of nonalcoholic fatty liver disease-related hepatocellular carcinoma.

International journal of cancer - 1 Dec 2016

Ki Kim Soo, Ueda Yoshihide, Hatano Etsuro, Kakiuchi Nobuyuki, Takeda Haruhiko, Goto Tomoyuki, Shimizu Takahiro, Yoshida Kenichi, Ikura Yoshihiro, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Miyano Satoru, Uemoto Shinji, Chiba Tsutomu, Ogawa Seishi, Marusawa Hiroyuki

Abstract excerpt

The number of patients with nonalcoholic fatty liver disease (NAFLD)-related hepatocellular carcinoma (HCC) is increasing. To understand the molecular features of the tumor phenotype, we aimed to clarify the overall landscape of genetic aberrations accumulated in NAFLD-related HCC. Of 247 HCC patients who underwent hepatectomy during 2010 to 2014 at a single center in Japan, 10 were diagnosed with NAFLD-HCC based...

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Topics

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Share to Carcinogenesis
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Deletion

Share to Chromosomes, Human, Pair 8

Share to Liver Neoplasms

Share to Non-alcoholic Fatty Liver Disease

Share to Promoter Regions, Genetic

Share to Telomerase

Source

Identifiers

PMID: 27511114
DOI: 10.1002/ijc.30379

Genes

TERT
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TERT promoter mutations and chromosome 8p loss are characteristic of nonalcoholic fatty liver disease-related hepatocellular carcinoma.PMID 27511114Read ↗

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