Article
Telomerase reverse transcriptase promoter mutations in hepatitis B virus-associated hepatocellular carcinoma.
Oncotarget - 10 May 2016
Yang Xunjun, Guo Xiuchan, Chen Yao, Chen Guorong, Ma Yin, Huang Kate, Zhang Yuning, Zhao Qiongya, Winkler Cheryl A, An Ping, Lyu Jianxin
Abstract excerpt
Telomerase reverse transcriptase (TERT) promoter mutations are among the most frequent noncoding somatic mutations in multiple cancers, including hepatocellular carcinoma (HCC). The clinical and pathological implications of TERT promoter mutations in hepatitis B virus (HBV)-associated HCC have not been resolved. To investigate TERT promoter mutations, protein expression, and their clinical-pathological...
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