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Article

Frequent somatic TERT promoter mutations and CTNNB1 mutations in hepatocellular carcinoma.

Oncotarget - 25 Oct 2016

Lee Seung Eun, Chang Seong-Hwan, Kim Wook Youn, Lim So Dug, Kim Wan Seop, Hwang Tea Sook, Han Hye Seung

Abstract excerpt

Genetic alterations of TERT and CTNNB1 have been documented in hepatocellular carcinoma. TERT promoter mutations are the earliest genetic events in the multistep process of hepatocarcinogenesis related to cirrhosis. However, analyses of TERT promoter and CTNNB1 mutations in hepatocellular carcinoma tumor samples have not been performed in the Korean population, where hepatitis B virus-related hepatocellular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27661004
DOI: 10.18632/oncotarget.12121
PMCID: PMC5342476

Genes

TERT
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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