Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Geographic and Viral Etiology Patterns of TERT Promoter and CTNNB1 Exon 3 Mutations in Hepatocellular Carcinoma: A Comprehensive Review

22 Mar 2025

Abstract excerpt

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and a leading cause of cancer-related mortality worldwide. Genetic alterations play a critical role in hepatocarcinogenesis, with mutations in the telomerase reverse transcriptase promoter (TERTp) and CTNNB1 exon 3 representing two of the most frequently reported somatic events in HCC. However, the frequency and distribution of these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to DNA Repair Mechanisms
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40243493
DOI: 10.3390/ijms26072889

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Geographic and Viral Etiology Patterns of TERT Promoter and CTNNB1 Exon 3 Mutations in Hepatocellular Carcinoma: A Comprehensive ReviewPMID 40243493Read ↗

Frequency and geographic distribution of TERT promoter mutations in primary hepatocellular carcinomaSemantic proximity Read ↗

Tumor specific mutations in TERT promoter and CTNNB1 gene in hepatitis B and hepatitis C related hepatocellular carcinoma.Semantic proximity Read ↗

TERT Promoter Mutations Combined with TP53 Mutations as Potential Biomarkers for Hepatocellular Carcinoma Recurrence and PrognosisSemantic proximity Read ↗

Frequent somatic TERT promoter mutations and CTNNB1 mutations in hepatocellular carcinoma.Semantic proximity Read ↗

Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features.Semantic proximity Read ↗

TERT-TP53 mutations: a novel biomarker pair for hepatocellular carcinoma recurrence and prognosisSemantic proximity Read ↗

TERT promoter mutations in primary liver tumors.Semantic proximity Read ↗

Genomic landscape of hepatocarcinogenesis.Semantic proximity Read ↗

Telomerase reverse transcriptase mutations in plasma DNA in patients with hepatocellular carcinoma or cirrhosis: Prevalence and risk factorsSemantic proximity Read ↗

Genetic Landscape and Biomarkers of Hepatocellular Carcinoma.Semantic proximity Read ↗

TERT promoter mutation predicts the prognosis value of patients with HBV- related HCC who underwent hepatectomySemantic proximity Read ↗

Global Epidemiology and Genetics of Hepatocellular CarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.