Article
SLCO1B1 gene polymorphisms do not influence plasma rifampicin concentrations in a South Indian population.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Sept 2016
Ramesh K, Hemanth Kumar A K, Kannan T, Vijayalakshmi R, Sudha V, Manohar Nesakumar S, Bharathiraja T, Lavanya J, Swaminathan S, Ramachandran G
Abstract excerpt
OBJECTIVE: To determine the effect of SLCO1B1 gene polymorphisms (rs11045819, rs4149032 and rs4149033) on rifampicin (RMP) concentrations in adult tuberculosis (TB) patients from south India. METHODS: We genotyped adult TB patients for three SLCO1B1 gene polymorphisms-rs11045819, rs4149032 and -and compared 2-h post-dosing RMP concentrations of the different genotypes for each of the polymorphisms....
