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Article

Role of vitamin D pathway gene polymorphisms on rifampicin plasma and intracellular pharmacokinetics.

Pharmacogenomics - 1 Jun 2017

Allegra Sarah, Fatiguso Giovanna, Calcagno Andrea, Baietto Lorena, Motta Ilaria, Favata Fabio, Cusato Jessica, Bonora Stefano, Di Perri Giovanni, D'Avolio Antonio

Abstract excerpt

AIM: We retrospectively evaluate the pharmacogenetic role of single nucleotide polymorphisms involved in rifampicin transport (SLCO1B1, MDR1 and PXR genes) and vitamin D (VDR, CYP24A1 and CYP27B1 genes) metabolism and activity on drug plasma and intracellular concentrations. PATIENTS & METHODS: Rifampicin Cmax and Ctrough were measured at weeks 2 and 4 using Ultra-Performance Liquid Chromatography-tandem mass...

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Source

Identifiers

PMID: 28594304
DOI: 10.2217/pgs-2017-0176

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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