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Article

DJ-1/Park7 Sensitive Na+ /H+ Exchanger 1 (NHE1) in CD4+ T Cells.

Journal of cellular physiology - 1 Nov 2017

Zhou Yuetao, Shi Xiaolong, Chen Hong, Zhang Shaqiu, Salker Madhuri S, Mack Andreas F, Föller Michael, Mak Tak W, Singh Yogesh, Lang Florian

Abstract excerpt

DJ-1/Park7 is a redox-sensitive chaperone protein counteracting oxidation and presumably contributing to the control of oxidative stress responses and thus inflammation. DJ-1 gene deletion exacerbates the progression of Parkinson's disease presumably by augmenting oxidative stress. Formation of reactive oxygen species (ROS) is paralleled by activation of the Na+ /H+ exchanger 1 (NHE1). ROS formation in CD4+ T...

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Identifiers

PMID: 27509531
DOI: 10.1002/jcp.25516

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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