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Article

DJ-1 is indispensable for the S-nitrosylation of Parkin, which maintains function of mitochondria

9 Mar 2020

Abstract excerpt

The DJ-1 gene, a causative gene for familial Parkinson's disease (PD), has been reported to have various functions, including transcriptional regulation, antioxidant response, and chaperone and protease functions; however, the molecular mechanism associated with the pathogenesis of PD remains elusive. To further explore the molecular function of DJ-1 in the pathogenesis of PD, we compared protein expression...

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PMID: 32152416
DOI: 10.1038/s41598-020-61287-6

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