Article
Protein DJ-1 and its anti-oxidative stress function play an important role in renal cell mediated response to profibrotic agents.
Molecular bioSystems - 24 May 2016
Eltoweissy Marwa, Dihazi Gry H, Müller Gerhard A, Asif Abdul R, Dihazi Hassan
Abstract excerpt
In the pathogenesis of renal fibrosis, oxidative stress (OS) enhances the production of reactive oxygen species (ROS) leading to sustained cell growth, inflammation, excessive tissue remodelling and accumulation, which results in the development and acceleration of renal damage. In our previous work (Eltoweissy et al., 2011) we established protein DJ-1 (PARK7) as an important ROS scavenger and key player in renal...
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