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Article

Prognostic relevance of caspase 8 -652 6N InsDel and Asp302His polymorphisms for breast cancer.

BMC cancer - 9 Aug 2016

Kuhlmann J D, Bankfalvi A, Schmid K W, Callies R, Kimmig R, Wimberger P, Siffert W, Bachmann H S

Abstract excerpt

BACKGROUND: The minor allele of two caspase 8 polymorphisms, namely CASP8 -652 6N InsDel (rs3834129) and CASP8 Asp302His (rs1045485), were repeatedly associated with reduced breast cancer susceptibility. Contrarily, the presence of the -652 6N Del or the CASP8 302His variant was reported to be an unfavorable prognostic factor in colorectal cancer or neuroblastoma. However, prognostic relevance of these genetic...

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Identifiers

PMID: 27507139
DOI: 10.1186/s12885-016-2662-x
PMCID: PMC4977759

Genes

CASP8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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