A breast cancer risk haplotype in the caspase-8 gene.

doi:10.1158/0008-5472.CAN-08-4266

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Article

A breast cancer risk haplotype in the caspase-8 gene.

Cancer research - 1 Apr 2009

Shephard Neil Duncan, Abo Ryan, Rigas Sushila Harkisandas, Frank Bernd, Lin Wei-Yu, Brock Ian Wallace, Shippen Adam, Balasubramanian Sabapathy Prakash, Reed Malcolm Walter Ronald, Bartram Claus Rainer, Meindl Alfons, Schmutzler Rita Katharina, Engel Christoph, Burwinkel Barbara, Cannon-Albright Lisa Anne, Allen-Brady Kristina, Camp Nicola Jane, Cox Angela

Abstract excerpt

Recent large-scale studies have been successful in identifying common, low-penetrance variants associated with common cancers. One such variant in the caspase-8 (CASP8) gene, D302H (rs1045485), has been confirmed to be associated with breast cancer risk, although the functional effect of this polymorphism (if any) is not yet clear. In order to further map the CASP8 gene with respect to breast cancer...

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Identifiers

PMID: 19318553
DOI: 10.1158/0008-5472.CAN-08-4266
PMCID: PMC2730164

Genes

CASP8

Variants

rs1045485

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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