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Article

Association of two CASP8 polymorphisms with breast cancer risk: a meta-analysis.

Breast cancer research and treatment - 1 Feb 2010

Sergentanis Theodoros N, Economopoulos Konstantinos P

Abstract excerpt

Caspase-8 (CASP8) is an initiator caspase implicated in the process of apoptosis in breast cancer cells. Attention has been drawn upon two polymorphisms: CASP8 D302H (rs1045485) and, more recently, CASP8 -652 6N del (rs3834129). The CASP8 -652 6N del polymorphism remains an open field, as studies are controversial. This meta-analysis aims to examine: (i) the association between CASP8 -652 6N del and breast cancer...

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Source

Identifiers

PMID: 19629679
DOI: 10.1007/s10549-009-0471-5

Genes

CASP8

Variants

rs1045485

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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