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Article

Genetic contribution of caspase-8 variants and haplotypes to breast cancer risk and prognosis: a case-control study in Iran.

BMC medical genomics - 4 Apr 2023

Afzaljavan Fahimeh, Vahednia Elham, Barati Bagherabad Matineh, Vakili Fatemeh, Moezzi Atefeh, Hosseini Azar, Homaei Shandiz Fatemeh, Kooshyar Mohammad Mahdi, Nassiri Mohammadreza, Pasdar Alireza

Abstract excerpt

PURPOSE: Multiple genome-wide and candidate-gene association studies have been conducted to search for common risk variants of breast cancer. Recent large meta-analyses and consolidating evidence have highlighted the role of the caspase-8 gene in breast cancer pathogenesis. Therefore, this study aimed to identify common variations and haplotypes associated with risk and overall survival of breast cancer with...

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Identifiers

PMID: 37016353
DOI: 10.1186/s12920-023-01484-0
PMCID: PMC10071634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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