Bi-directional PCR allele-specific amplification (bi-PASA) for detection of caspase-8 -652 6N ins/del promoter polymorphism (rs3834129) in breast cancer.

doi:10.1016/j.gene.2012.05.043

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Article

Bi-directional PCR allele-specific amplification (bi-PASA) for detection of caspase-8 -652 6N ins/del promoter polymorphism (rs3834129) in breast cancer.

Gene - 15 Aug 2012

Hashemi Mohammad, Eskandari-Nasab Ebrahim, Fazaeli Aliakbar, Rezaei Hamzeh, Mashhadi Mohammad Ali, Arbabi Farshid, Taheri Mohsen

Abstract excerpt

Caspase-8 (CASP8) plays a critical role in regulating apoptosis, and its functional polymorphisms may modify cancer risk. We investigated the possible association between CASP8 -652 6N ins/del (rs3834129) and the risk of breast cancer in a sample of Iranian population. This case-control study was done on 236 breast cancer patients and 203 cancer free healthy female. We designed a rapid and simple bi-directional...

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PMID: 22659694
DOI: 10.1016/j.gene.2012.05.043

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CASP8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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