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Article

Nucleotide variation of sFRP5 gene is not associated with obesity in children and adolescents.

Molecular biology reports - 1 Oct 2016

Van Camp Jasmijn K, Beckers Sigri, Zegers Doreen, Verhulst Stijn L, Van Hoorenbeeck Kim, Massa Guy, Verrijken An, Desager Kristine N, Van Gaal Luc F, Van Hul Wim

Abstract excerpt

Because sFRP5 was shown to be an important extracellular modulator of the Wnt pathway, regulating adipogenesis, we wanted to investigate the role of sFRP5 variants in human, monogenic obesity by performing mutation analysis. We screened the complete sFRP5 coding region in 622 obese children and adolescents and 503 lean control individuals by high-resolution melting curve analysis and direct sequencing. We found a...

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PMID: 27497818
DOI: 10.1007/s11033-016-4050-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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