Article
Common genetic variation in sFRP5 is associated with fat distribution in men.
Endocrine - 1 Aug 2014
Van Camp J K, Beckers S, Zegers D, Verrijken A, Van Gaal L F, Van Hul W
Abstract excerpt
Considering the role of sFRP5 in Wnt signalling, an important group of pathways regulating adipogenesis and inflammation, we performed a genetic association study on sFRP5 polymorphisms in a population of obese and lean individuals. Using information from the HapMap, two tagSNPs were identified in the sFRP5 gene region and genotyped on a population of 1,014 obese, non-diabetic individuals and 606 lean controls....
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