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Article

The STK33-linked SNP rs4929949 is associated with obesity and BMI in two independent cohorts of Swedish and Greek children.

PloS one - 1 Jan 2013

Rask-Andersen Mathias, Moschonis George, Chrousos George P, Marcus Claude, Dedoussis George V, Fredriksson Robert, Schiöth Helgi B

Abstract excerpt

Recent genome wide association studies (GWAS) have identified a locus on chromosome 11p15.5, closely associated with serine/threonine kinase 33 (STK33), to be associated with body mass. STK33, a relatively understudied protein, has been linked to KRAS mutation-driven cancers and explored as a potential antineoplastic drug target. The strongest association with body mass observed at this loci in GWAS was...

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Identifiers

PMID: 23967198
DOI: 10.1371/journal.pone.0071353
PMCID: PMC3744548

Genes

STK33
KRAS

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