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Article

Mutation analysis of WNT10B in obese children, adolescents and adults.

Endocrine - 1 Aug 2013

Van Camp Jasmijn K, Zegers Doreen, Verhulst Stijn L, Van Hoorenbeeck Kim, Massa Guy, Verrijken An, Desager Kristine N, Van Gaal Luc F, Van Hul Wim, Beckers Sigri

Abstract excerpt

Wingless-type MMTV integration site family, member 10B (WNT10B) is an activator of the Wnt pathway. The Wnt pathway is known to play an important role in maintenance and differentiation of stem cells and has been implicated in the origination of obesity. To evaluate the role of genetic variation in WNT10B in obesity further, we performed a mutation analysis on Belgian obese patients and control subjects. A...

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PMID: 23104151
DOI: 10.1007/s12020-012-9824-7

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