Article
TPH2 -703G/T SNP may have important effect on susceptibility to suicidal behavior in major depression.
Progress in neuro-psychopharmacology & biological psychiatry - 30 Apr 2009
Yoon Ho-Kyoung, Kim Yong-Ku
Abstract excerpt
BACKGROUND: Serotonergic system-related genes can be good candidate genes for both major depressive disorder (MDD) and suicidal behavior. In this study, we aimed to investigate the association of serotonin 2A receptor gene -1438A/G SNP (HTR2A -1438A/G), tryptophan hydroxylase 2 gene -703G/T SNP (TPH2 -703G/T) and serotonin 1A receptor C-1019G (HTR1A C-1019G) with suicidal behavior. METHODS: One hundred and eighty...
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