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Article

Frequent detection of PIK3CA mutations in single circulating tumor cells of patients suffering from HER2-negative metastatic breast cancer.

Molecular oncology - 1 Oct 2016

Gasch Christin, Oldopp Theresa, Mauermann Oliver, Gorges Tobias M, Andreas Antje, Coith Cornelia, Müller Volkmar, Fehm Tanja, Janni Wolfgang, Pantel Klaus, Riethdorf Sabine

Abstract excerpt

Modern technologies enable detection and characterization of circulating tumor cells (CTC) in peripheral blood samples. Thus, CTC have attracted interest as markers for therapeutic response in breast cancer. First studies have incorporated CTC analyses to guide therapeutic interventions and stratification of breast cancer patients. Aim of this study was to analyze characteristic features of CTC as biomarker for...

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Identifiers

PMID: 27491860
DOI: 10.1016/j.molonc.2016.07.005
PMCID: PMC5423206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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