Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational analysis of single circulating tumor cells by next generation sequencing in metastatic breast cancer.

Oncotarget - 3 May 2016

De Luca Francesca, Rotunno Giada, Salvianti Francesca, Galardi Francesca, Pestrin Marta, Gabellini Stefano, Simi Lisa, Mancini Irene, Vannucchi Alessandro Maria, Pazzagli Mario, Di Leo Angelo, Pinzani Pamela

Abstract excerpt

Circulating Tumor Cells (CTCs) represent a "liquid biopsy" of the tumor potentially allowing real-time monitoring of cancer biology and therapies in individual patients.The purpose of the study was to explore the applicability of a protocol for the molecular characterization of single CTCs by Next Generation Sequencing (NGS) in order to investigate cell heterogeneity and provide a tool for a personalized medicine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Neoplastic Cells, Circulating

Share to Prognosis

Share to Single-Cell Analysis

Share to Survival Rate

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 27034166
DOI: 10.18632/oncotarget.8431
PMCID: PMC5041968

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of single circulating tumor cells by next generation sequencing in metastatic breast cancer.PMID 27034166Read ↗

Single circulating tumor cell sequencing as an advanced tool in cancer management.Semantic proximity Read ↗

The diagnostic potential of mutation detection from single circulating tumor cells in cancer patients.Semantic proximity Read ↗

Feasibility of a workflow for the molecular characterization of single cells by next generation sequencingSemantic proximity Read ↗

Targeted Next-Generation Sequencing of Circulating Tumor DNA Mutations among Metastatic Breast Cancer Patients.Semantic proximity Read ↗

Dissecting Molecular Heterogeneity of Circulating Tumor Cells (CTCs) from Metastatic Breast Cancer Patients through Copy Number Aberration (CNA) and Single Nucleotide Variant (SNV) Single Cell AnalysisSemantic proximity Read ↗

Targeted Next-Generation Sequencing of Circulating Tumor DNA Mutations among Metastatic Breast Cancer PatientsSemantic proximity Read ↗

Evaluation and consequences of heterogeneity in the circulating tumor cell compartment.Semantic proximity Read ↗

Mutation analysis in individual circulating tumor cells depicts intratumor heterogeneity in melanoma.Semantic proximity Read ↗

Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts.Semantic proximity Read ↗

Frequent detection of PIK3CA mutations in single circulating tumor cells of patients suffering from HER2-negative metastatic breast cancer.Semantic proximity Read ↗

Circulating tumor cells in breast cancer: functional heterogeneity, pathogenetic and clinical aspects.Semantic proximity Read ↗

Circulating tumor DNA and circulating tumor cells in metastatic triple negative breast cancer patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.