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Article

Autophagic flux regulates microglial phenotype according to the time of oxygen-glucose deprivation/reperfusion.

International immunopharmacology - 1 Oct 2016

Xia Cong-Yuan, Zhang Shuai, Chu Shi-Feng, Wang Zhen-Zhen, Song Xiu-Yun, Zuo Wei, Gao Yan, Yang Peng-Fei, Chen Nai-Hong

Abstract excerpt

Microglial phenotype alternation is a potential novel pathogenic mechanism for cerebral ischemia. Cerebral ischemia induced autophagy aggravates inflammation and neural injury. However, the effect of autophagy in the modulation of microglial phenotype is still unknown. In this study, we investigated the role of autophagic flux in the alternation of microglial phenotype following oxygen glucose...

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PMID: 27474951
DOI: 10.1016/j.intimp.2016.06.030

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BDNF
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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