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Article

Metformin-dependent variation of microglia phenotype dictates pericytes maturation under oxygen-glucose deprivation.

Tissue barriers - 2 Oct 2022

Geranmayeh Mohammad Hossein, Rahbarghazi Reza, Saeedi Nazli, Farhoudi Mehdi

Abstract excerpt

Blood-brain barrier resident cells are in the frontline of vascular diseases. To maintain brain tissue homeostasis, a series of cells are integrated regularly to form the neurovascular unit. It is thought that microglia can switch between M1/M2 phenotypes after the initiation of different pathologies. The existence of transition between maturity and stemness features in pericytes could maintain blood-brain...

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Identifiers

PMID: 34983297
DOI: 10.1080/21688370.2021.2018928
PMCID: PMC9620990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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