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Article

Investigation of N-cadherin/β-catenin expression in adrenocortical tumors.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2016

Rubin Beatrice, Regazzo Daniela, Redaelli Marco, Mucignat Carla, Citton Marilisa, Iacobone Maurizio, Scaroni Carla, Betterle Corrado, Mantero Franco, Fassina Ambrogio, Pezzani Raffaele, Boscaro Marco

Abstract excerpt

β-catenin is a multifunctional protein; it is a key component of the Wnt signaling, and it plays a central role in cadherin-based adhesions. Cadherin loss promotes tumorigenesis by releasing membrane-bound β-catenin, hence stimulating Wnt signaling. Cadherins seem to be involved in tumor development, but these findings are limited in adrenocortical tumors (ACTs). The objective of this study was to evaluate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27468715
DOI: 10.1007/s13277-016-5257-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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