Article
Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting.
Journal of nanobiotechnology - 25 Jul 2016
Plissonneau Marie, Pansieri Jonathan, Heinrich-Balard Laurence, Morfin Jean-François, Stransky-Heilkron Nathalie, Rivory Pascaline, Mowat Pierre, Dumoulin Mireille, Cohen Richard, Allémann Éric, Tόth Éva, Saraiva Maria Joao, Louis Cédric, Tillement Olivier, Forge Vincent, Lux François, Marquette Christel
Abstract excerpt
BACKGROUND: Amyloidoses are characterized by the extracellular deposition of insoluble fibrillar proteinaceous aggregates highly organized into cross-β structure and referred to as amyloid fibrils. Nowadays, the diagnosis of these diseases remains tedious and involves multiple examinations while an early and accurate protein typing is crucial for the patients' treatment. Routinely used neuroimaging techniques...
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