Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aptamers targeting amyloidogenic proteins and their emerging role in neurodegenerative diseases

9 Dec 2021

Abstract excerpt

Aptamers are oligonucleotides selected from large pools of random sequences based on their affinity for bioactive molecules and are used in similar ways to antibodies. Aptamers provide several advantages over antibodies, including their small size, facile, large-scale chemical synthesis, high stability, and low immunogenicity. Amyloidogenic proteins, whose aggregation is relevant to neurodegenerative diseases,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Prion Diseases and Protein Misfolding
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34896392
DOI: 10.1016/j.jbc.2021.101478

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aptamers targeting amyloidogenic proteins and their emerging role in neurodegenerative diseasesPMID 34896392Read ↗

Aptamers Selected for Recognizing Amyloid β-protein—A Case for Cautious OptimismSemantic proximity Read ↗

Identification and Engineering of Aptamers for Theranostic Application in Human Health and DisordersSemantic proximity Read ↗

Nanobody Therapeutics in Alzheimer’s Disease: From Molecular Mechanisms to Translational ApproachesSemantic proximity Read ↗

Therapeutic Applications of AptamersSemantic proximity Read ↗

Functional Selection of Tau Oligomerization‐Inhibiting AptamersSemantic proximity Read ↗

Biologics as Therapeutical Agents Under Perspective Clinical Studies for Alzheimer’s DiseaseSemantic proximity Read ↗

Aptamers: An Emerging Class of Molecules That Rival Antibodies in DiagnosticsSemantic proximity Read ↗

Antisense Oligonucleotide Therapy for the Nervous System: From Bench to Bedside with Emphasis on Pediatric NeurologySemantic proximity Read ↗

Amyloid-β Peptide-specific DARPins as a Novel Class of Potential Therapeutics for Alzheimer DiseaseSemantic proximity Read ↗

A Highlight of Recent Advances in Aptamer Technology and Its ApplicationSemantic proximity Read ↗

Inhibition of α-Synuclein Seeding-Dependent Aggregation by ssDNA Aptamers Specific to C-Terminally Truncated α-Synuclein FibrilsSemantic proximity Read ↗

Nucleic Acid-Based Aptamers: Applications, Development and Clinical TrialsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.