Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Superparamagnetic nanoparticle-enhanced MRI of Alzheimer's disease plaques and activated microglia in 3X transgenic mouse brains: Contrast optimization.

Journal of magnetic resonance imaging : JMRI - 1 Aug 2017

Tafoya Marissa A, Madi Saaussan, Sillerud Laurel O

Abstract excerpt

PURPOSE: To optimize magnetic resonance imaging (MRI) of antibody-conjugated superparamagnetic nanoparticles for detecting amyloid-β plaques and activated microglia in a 3X transgenic mouse model of Alzheimer's disease. MATERIALS AND METHODS: Ten 3X Tg mice were fed either chow or chow containing 100 ppm resveratrol. Four brains, selected from animals injected with either anti-amyloid targeted superparamagnetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloidogenic Proteins
Share to Contrast Media

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ferric Compounds

Share to Metal Nanoparticles

Share to Micelles

Share to Plaque, Amyloid

Share to Resveratrol

Share to Stilbenes

Source

Identifiers

PMID: 27875002
DOI: 10.1002/jmri.25563

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Superparamagnetic nanoparticle-enhanced MRI of Alzheimer's disease plaques and activated microglia in 3X transgenic mouse brains: Contrast optimization.PMID 27875002Read ↗

Optical and SPION-enhanced MR imaging shows that trans-stilbene inhibitors of NF-κB concomitantly lower Alzheimer's disease plaque formation and microglial activation in AβPP/PS-1 transgenic mouse brain.Semantic proximity Read ↗

<i>In Vivo</i>Detection of Age- and Disease-Related Increases in Neuroinflammation by<sup>18</sup>F-GE180 TSPO MicroPET Imaging in Wild-Type and Alzheimer's Transgenic MiceSemantic proximity Read ↗

Microglia-Specific Molecular Magnetic Resonance Imaging Probe Enables Noninvasive Separation of Parkinsonian Mice from ControlsSemantic proximity Read ↗

Intravenous anti-Aβ immunotherapy acutely increases cerebral amyloid angiopathy and vascular damages in APOE4 miceSemantic proximity Read ↗

Tracking tau fibrillogenesis and consequent primary phagocytosis of neurons mediated by microglia in a living tauopathy modelSemantic proximity Read ↗

Visualization of brain amyloid and microglial activation in mouse models of Alzheimer's disease.Semantic proximity Read ↗

Detecting amyloid-β plaques in Alzheimer's disease.Semantic proximity Read ↗

Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting.Semantic proximity Read ↗

Pre-clinical imaging of transgenic mouse models of neuroblastoma using a dedicated 3-element solenoid coil on a clinical 3T platform.Semantic proximity Read ↗

In vivo Assessment of Neuroinflammation in 4-Repeat TauopathiesSemantic proximity Read ↗

Targeting Soluble Amyloid-Beta Oligomers With a Novel NanobodySemantic proximity Read ↗

A Metal-Free Method for Producing MRI Contrast at Amyloid-β.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.