Article

Non-micellar ganglioside GM1 induces an instantaneous conformational change in Aβ <sub>42</sub> leading to the modulation of the peptide amyloid-fibril pathway

2023-05-14

Abstract excerpt

Alzheimer’s disease is a progressive degenerative condition that mainly affects cognition and memory. Recently, distinct clinical and neuropathological phenotypes have been identified in AD. Studies revealed that structural variation in Aβ fibrillar aggregates correlates with distinct disease phenotypes. Moreover, environmental surroundings, including other biomolecules such as proteins and lipids, have been shown...

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Literature Corpus work: e7687cba-e6a5-5c16-a2e1-6bf2a24efb70
DOI: 10.1101/2023.05.12.540574

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Non-micellar ganglioside GM1 induces an instantaneous conformational change in Aβ <sub>42</sub> leading to the modulation of the peptide amyloid-fibril pathwayDOI 10.1101/2023.05.12.540574Read

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