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Article

GRIN3B missense mutation as an inherited risk factor for schizophrenia: whole-exome sequencing in a family with a familiar history of psychotic disorders.

Genetics research - 30 Jan 2017

Hornig Tobias, Grüning Björn, Kundu Kousik, Houwaart Torsten, Backofen Rolf, Biber Knut, Normann Claus

Abstract excerpt

Glutamate is the most important excitatory neurotransmitter in the brain. The N-methyl-D-aspartate (NMDA) receptor is a glutamate-gated ionotropic cation channel that is composed of several subunits and modulated by a glycine binding site. Many forms of synaptic plasticity depend on the influx of calcium ions through NMDA receptors, and NMDA receptor dysfunction has been linked to a number of neuropsychiatric...

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Identifiers

PMID: 28132660
DOI: 10.1017/S0016672316000148
PMCID: PMC6865172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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