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Article

Significant association between the genetic variations in the 5' end of the N-methyl-D-aspartate receptor subunit gene GRIN1 and schizophrenia.

Biological psychiatry - 15 Apr 2006

Zhao Xinzhi, Li Huafang, Shi Yongyong, Tang Ruqi, Chen Wuyan, Liu Jixia, Feng Guoyin, Shi Jianguo, Yan Lijuan, Liu Huijun, He Lin

Abstract excerpt

BACKGROUND: N-methyl-D-aspartate (NMDA) receptors play important roles in many neurophysiological processes. Evidence from previous studies indicate that NMDA receptors contribute to the pathophysiology of schizophrenia. Two NMDA receptor subunit genes, GRIN1 and GRIN2A, are both good candidate genes for schizophrenia. METHOD: We genotyped five single nucleotide polymorphisms (SNPs) in GRIN1 and two in GRIN2A in...

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Source

Identifiers

PMID: 16476413
DOI: 10.1016/j.biopsych.2005.10.023

Genes

GRIN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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