Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

rDNA Copy Number Variants Are Frequent Passenger Mutations in Saccharomyces cerevisiae Deletion Collections and de Novo Transformants.

G3 (Bethesda, Md.) - 8 Sept 2016

Kwan Elizabeth X, Wang Xiaobin S, Amemiya Haley M, Brewer Bonita J, Raghuraman M K

Abstract excerpt

The Saccharomyces cerevisiae ribosomal DNA (rDNA) locus is known to exhibit greater instability relative to the rest of the genome. However, wild-type cells preferentially maintain a stable number of rDNA copies, suggesting underlying genetic control of the size of this locus. We performed a screen of a subset of the Yeast Knock-Out (YKO) single gene deletion collection to identify genetic regulators of this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetates
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Replication

Share to DNA, Ribosomal

Share to Gene Deletion

Share to Gene Knockout Techniques

Share to Genome, Fungal

Share to Ribosomes

Source

Open in PubMed Open full text

Identifiers

PMID: 27449518
DOI: 10.1534/g3.116.030296
PMCID: PMC5015940

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

rDNA Copy Number Variants Are Frequent Passenger Mutations in Saccharomyces cerevisiae Deletion Collections and de Novo Transformants.PMID 27449518Read ↗

Contribution of Spontaneous Mutations to Quantitative and Molecular Variation at the Highly Repetitive rDNA Locus in Yeast.Semantic proximity Read ↗

Hotspot of <i>de novo</i> telomere addition stabilizes linear amplicons in yeast grown in sulfate-limiting conditionsSemantic proximity Read ↗

Repetitive sequence variation and dynamics in the ribosomal DNA array of Saccharomyces cerevisiae as revealed by whole-genome resequencing.Semantic proximity Read ↗

Characterization of systemic genomic instability in budding yeast.Semantic proximity Read ↗

Spontaneous rDNA copy number variation modulates Sir2 levels and epigenetic gene silencing.Semantic proximity Read ↗

Genomic copy-number loss is rescued by self-limiting production of DNA circlesSemantic proximity Read ↗

Ribosomal DNA copy number loss and sequence variation in cancer.Semantic proximity Read ↗

Diversity and distribution of the subtelomeric Y’ elements across <i>Saccharomyces cerevisiae</i> strainsSemantic proximity Read ↗

Spontaneous Changes in Ploidy Are Common in Yeast.Semantic proximity Read ↗

Defects in the NuA4 acetyltransferase complex increase stability of the ribosomal RNA gene and extend replicative lifespan.Semantic proximity Read ↗

Genome instability footprint under rapamycin and hydroxyurea treatmentsSemantic proximity Read ↗

Transgenerational dynamics of rDNA copy number in Drosophila male germline stem cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.