Article
Repetitive sequence variation and dynamics in the ribosomal DNA array of Saccharomyces cerevisiae as revealed by whole-genome resequencing.
Genome research - 1 Apr 2009
James Stephen A, O'Kelly Michael J T, Carter David M, Davey Robert P, van Oudenaarden Alexander, Roberts Ian N
Abstract excerpt
Ribosomal DNA (rDNA) plays a key role in ribosome biogenesis, encoding genes for the structural RNA components of this important cellular organelle. These genes are vital for efficient functioning of the cellular protein synthesis machinery and as such are highly conserved and normally present in high copy numbers. In the baker's yeast Saccharomyces cerevisiae, there are more than 100 rDNA repeats located at a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
